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Treatment of gustatory hyperlacrimation (crocodile tears) with injection of botulinum toxin into the lacrimal gland

Eye (2002) 16, 705–709. doi: 10.1038/sj.eye.6700230 Presented as a poster at the Royal College of Ophthalmologists Congress 2000. The authors received no funding for this work F J Montoya1, C E Riddell1, R Caesar1 and S Hague1 1Oxford Eye Hospital Radcliffe Infirmary Oxford, UK Correspondence: S Hague, Oxford Eye Hospital Woodstock Road Oxford OX2 6HE, UK Tel: ++44 (0)1865 311188 Fax: ++44 (0) 1865 224013 E-mail: Jean.Butler@orh.nhs.uk Received 19 December 2000; Accepted 18 May 2001. Top of pageAbstract Purpose To establish the efficacy and safety of botulinum toxin in the treatment of Crocodile Tear Syndrome and record any possible complications. Methods Four patients with unilateral aberrant VII cranial nerve regeneration following an episode of facial paralysis consented to be included in this study after a comprehensive explanation of the procedure and possible complications was given. On average, an injection of 20 units of botulinum toxin type A (Dysport®) was given to the affect